Entries in research (10)
A film from the research and development for a series of works entitled 'Wasted'. This film is made for the BBC Big Screens and was made as part of DadaFest 09.
Pixie Dust explores the notion of limb regeneration for humans within the contexts of science, sport, disability and super-ability.
The title Pixie Dust comes from the substance taken from the pigs gut matrix that is applied to wounds to prevent scarrification and therefore allow continual growth of the tissue – as used in finger regeneration (allegedly) it plays the nonreality and disney-fication of scientific research.
Mesenchymal stem cells (MSCs) resident in bone marrow are one of the most studied and clinically important populations of adult stem cells. Cells with, similar properties to these MSCs have been described in several different tooth tissues and the potential ease with which these dental MSCs could be obtained from patients has prompted great interest in these cells as a source of MSCs for cell-based therapeutics. In this review we address the current state of knowledge regarding these cells, their properties, origins, locations, functions and potential uses in tooth tissue engineering and repair. We discuss some of the key controversies and outstanding issues, not least of which whether dental stem cells actually exist.
The representation of science, medicine, and technology has been an emerging agenda item for cultural and media research in the last decade. In part, its importance arises out of a concern for the public understanding of science (PUoS), which has been a priority in governmental policy discussions. This paper discusses how the utilization of cyberspatial communities can address the challenge of developing a global engagement with science and ethics, by considering the case of genetic technology and the role of experts in public debate. It critically appraises the PUoS and suggests that a way of advancing its methodological assumptions is through developing a “Public Engagement with Ethics.” On this basis, concerns about scientific journalism are more effectively contextualized and enhance the possibility of ensuring that non-experts are aware of the importance of any scientific innovation.
The notion that teeth contain stem cells is based on the well-known repairing ability of dentin after injury. Dental stem cells have been isolated according to their anatomical locations, colony-forming ability, expression of stem cell markers, and regeneration of pulp/dentin structures in vivo. These dental-derived stem cells are currently under increasing investigation as sources for tooth regeneration and repair. Further attempts with bone marrow mesenchymal stem cells and embryonic stem cells have demonstrated the possibility of creating teeth from non-dental stem cells by imitating embryonic development mechanisms. Although, as in tissue engineering of other organs, many challenges remain, stem-cell-based tissue engineering of teeth could be a choice for the replacement of missing teeth in the future.